Gastroenterology Clinical Trials

Crohn's disease is a chronic inflammatory condition that can affect any part of the digestive tract, from the mouth to the anus. It most commonly involves the end of the small intestine (ileum) and the beginning of the large intestine (colon). The inflammation can penetrate deeply into the bowel walls, which can lead to complications such as strictures, fistulas, and abscesses. According to Crohn's & Colitis Foundation, millions of people worldwide are affected by this condition.

Ulcerative colitis (UC) is an inflammatory bowel disease characterized by chronic inflammation and ulceration of the colon and rectum. This condition typically affects the inner lining of the large intestine and can cause symptoms including abdominal pain, diarrhea, rectal bleeding, and urgency. UC follows a relapsing and remitting course with periods of active symptoms alternating with periods of remission. The National Institute of Diabetes and Digestive and Kidney Diseases provides comprehensive information about this condition.

Inflammatory bowel disease (IBD) is characterized by recurrent episodes of gastrointestinal inflammation resulting from an abnormal immune response. Consequently, this group primarily includes Crohn's disease and ulcerative colitis, affecting millions of people worldwide. These chronic conditions can significantly impact daily functioning and quality of life, requiring long-term management strategies.

Irritable bowel syndrome (IBS) is a common functional gastrointestinal disorder characterized by symptoms related to bowel function without any visible structural abnormalities. It primarily affects the large intestine and can cause abdominal pain, bloating, gas, diarrhea, and constipation. Consequently, IBS can significantly impact a person's quality of life and daily activities.